Exome Asset Management 13F annual report

Exome Asset Management is an investment fund managing more than $117 billion ran by Brianne Shergill. There are currently 53 companies in Mrs. Shergill’s portfolio. The largest investments include Eli Lilly & Co and Dr Reddys Labs Ltd, together worth $13.9 billion.

$117 billion Assets Under Management (AUM)

As of 7th August 2024, Exome Asset Management’s top holding is 9,700 shares of Eli Lilly & Co currently worth over $7.55 billion and making up 6.5% of the portfolio value. In addition, the fund holds 86,000 shares of Dr Reddys Labs Ltd worth $6.31 billion. The third-largest holding is BeiGene Ltd worth $5.76 billion and the next is Cigna worth $5.56 billion, with 15,300 shares owned.

Currently, Exome Asset Management's portfolio is worth at least $117 billion. The total portfolio value may be much higher due to cash assets that are not publicly disclosed such as fixed income, real estate, or cash equivalents.

Careers at Exome Asset Management

The Exome Asset Management office and employees reside in New York, New York. According to the last 13-F report filed with the SEC, Brianne Shergill serves as the Chief Compliance Officer at Exome Asset Management.

Recent trades

In the most recent 13F filing, Exome Asset Management revealed that it had opened a new position in Avidity Biosciences and bought 135,169 shares worth $3.45 billion. This means they effectively own approximately 0.1% of the company. Avidity Biosciences makes up 4.5% of the fund's Health Care sector allocation and has grown its share price by 419.7% in the past year.

The investment fund also strengthened its position in BeiGene Ltd by buying 24,000 additional shares. This makes their stake in BeiGene Ltd total 36,800 shares worth $5.76 billion. BeiGene Ltd dropped 8.3% in the past year.

On the other hand, there are companies that Exome Asset Management is getting rid of from its portfolio. Exome Asset Management closed its position in Immunogen on 14th August 2024. It sold the previously owned 186,900 shares for $5.54 billion. Brianne Shergill also disclosed a decreased stake in Dr Reddys Labs Ltd by approximately 0.1%. This leaves the value of the investment at $6.31 billion and 86,000 shares.

One of the smallest hedge funds

The two most similar investment funds to Exome Asset Management are Tenzing Global Management and M3 Advisory. They manage $115 billion and $115 billion respectively.


Brianne Shergill investment strategy

Exome Asset Management’s portfolio is diversified across 2 sectors. Currently, their heaviest sector is Health Care — making up 65.9% of the total portfolio value. The fund focuses on investments in the United States as 60.4% of the portfolio companies are based in the United States.

The majority of the companies in the fund’s portfolio are large-cap stocks. Stocks with a size of more than $10 billion in market cap make up 9% of the total holdings value. On the other hand, small-cap stocks make up only 7.5% of the portfolio. The average market cap of the portfolio companies is close to $9.89 billion.

The complete list of Exome Asset Management trades based on 13F SEC filings

These positions were updated on August 14th based on the fund’s latest 13F filing. Quickly find out what the most recently closed or increased positions are.

Security Shares Owned Value Allocation
Eli Lilly & Co
No change
9,700
$7,546,212,000 6.46%
Dr Reddys Labs Ltd
4.44%
86,000
$6,308,100,000 5.40%
BeiGene Ltd
187.50%
36,800
$5,755,152,000 4.93%
Cigna Group (The)
No change
15,300
$5,556,807,000 4.76%
Immunogen, Inc.
Closed
186,900
$5,541,585,000
Alpine Immune Sciences Inc
32.56%
117,000
$4,637,880,000 3.97%
TG Therapeutics Inc
13.28%
230,300
$3,502,863,000 3.00%
Avidity Biosciences, Inc.
Opened
135,169
$3,449,513,000 2.95%
Corbus Pharmaceuticals Hldgs
Opened
87,846
$3,447,077,000 2.95%
Dexcom Inc
No change
24,828
$3,443,644,000 2.95%
Centessa Pharmaceuticals Plc
Opened
274,900
$3,106,370,000 2.66%
Celldex Therapeutics Inc.
36.12%
71,100
$2,984,067,000 2.56%
Geron Corp.
45.98%
886,800
$2,926,440,000 2.51%
Aerovate Therapeutics Inc
Opened
98,485
$2,912,201,000 2.49%
Morphosys AG
Opened
154,800
$2,808,072,000 2.40%
Travere Therapeutics Inc
331.60%
362,487
$2,794,775,000 2.39%
Inhibrx, Inc.
Closed
73,158
$2,780,004,000
Structure Therapeutics Inc
Closed
68,100
$2,775,756,000
Rocket Pharmaceuticals Inc
Closed
91,800
$2,751,246,000
Krystal Biotech Inc
Opened
14,700
$2,615,571,000 2.24%
Intuitive Surgical Inc
No change
6,358
$2,537,414,000 2.17%
Tarsus Pharmaceuticals, Inc.
21.45%
66,300
$2,410,005,000 2.06%
Legend Biotech Corp
Closed
37,900
$2,280,443,000
Madrigal Pharmaceuticals Inc
40.16%
7,900
$2,109,616,000 1.81%
Inozyme Pharma, Inc.
Opened
273,413
$2,094,344,000 1.79%
Rhythm Pharmaceuticals Inc.
36.84%
45,603
$1,975,978,000 1.69%
Biohaven Ltd
Closed
45,467
$1,945,988,000
Insmed Inc
16.59%
71,700
$1,945,221,000 1.67%
Elevation Oncology Inc
Opened
369,322
$1,894,622,000 1.62%
Exact Sciences Corp.
Opened
26,700
$1,843,902,000 1.58%
Cytokinetics Inc
25.50%
26,008
$1,823,421,000 1.56%
Lantheus Holdings Inc
Closed
29,100
$1,804,200,000
Regenxbio Inc
Opened
84,470
$1,779,783,000 1.52%
Catalyst Pharmaceuticals Inc
Closed
105,500
$1,773,455,000
Biogen Inc
No change
8,200
$1,768,166,000 1.51%
Ocular Therapeutix Inc
Opened
193,600
$1,761,760,000 1.51%
Agios Pharmaceuticals Inc
Opened
59,902
$1,751,534,000 1.50%
Natera Inc
No change
18,650
$1,705,729,000 1.46%
Penumbra Inc
14.03%
7,353
$1,641,043,000 1.41%
Guardant Health Inc
Opened
79,000
$1,629,770,000 1.40%
Olema Pharmaceuticals, Inc.
Opened
143,400
$1,623,288,000 1.39%
Arrowhead Pharmaceuticals In
Opened
55,700
$1,593,020,000 1.36%
Shattuck Labs, Inc.
Closed
223,300
$1,592,129,000
Vertex Pharmaceuticals, Inc.
Closed
3,900
$1,586,871,000
BridgeBio Pharma Inc
25.04%
48,807
$1,509,112,000 1.29%
Terns Pharmaceuticals Inc
Opened
227,821
$1,494,506,000 1.28%
Marinus Pharmaceuticals Inc
Opened
163,100
$1,474,424,000 1.26%
Inari Med Inc
Opened
30,100
$1,444,198,000 1.24%
Quanterix Corp
Opened
59,650
$1,405,354,000 1.20%
Intra-Cellular Therapies Inc
28.27%
20,300
$1,404,760,000 1.20%
Immatics N.v
Closed
129,900
$1,367,847,000
Prothena Corp Plc
Closed
36,384
$1,322,195,000
Shockwave Med Inc
No change
4,000
$1,302,520,000 1.12%
VYNE Therapeutics Inc.
251.76%
415,434
$1,275,382,000 1.09%
Taysha Gene Therapies, Inc.
Closed
693,300
$1,227,141,000
Macrogenics Inc
Closed
125,900
$1,211,158,000
Regulus Therapeutics Inc
125.61%
402,504
$1,159,212,000 0.99%
IGM Biosciences, Inc.
Closed
135,596
$1,126,803,000
Q32 Bio Inc
Opened
65,021
$1,107,958,000 0.95%
Cabaletta Bio Inc
Closed
46,700
$1,060,090,000
Zai Lab Ltd
Opened
65,300
$1,046,106,000 0.90%
Enliven Therapeutics Inc
Opened
57,635
$1,013,800,000 0.87%
Mirati Therapeutics Inc
Closed
15,896
$933,890,000
Ventyx Biosciences Inc
Opened
163,922
$901,571,000 0.77%
Pliant Therapeutics, Inc.
Closed
49,580
$897,894,000
Ultragenyx Pharmaceutical In
Opened
17,800
$831,082,000 0.71%
Sage Therapeutics Inc
Closed
35,257
$764,019,000
Establishment Labs Holdings Inc
Closed
27,600
$714,564,000
Sutro Biopharma Inc
Closed
153,600
$658,944,000
EyePoint Pharmaceuticals Inc
Closed
26,400
$610,104,000
I-Mab
Opened
325,762
$605,917,000 0.52%
Moonlake Immunotherapeutics
Closed
9,744
$588,440,000
Procaps Group Sa
Closed
126,901
$516,487,000
Adagene Inc
Opened
155,383
$435,072,000 0.37%
Apellis Pharmaceuticals Inc
Closed
7,249
$433,925,000
Gracell Biotechnologies Inc.
Closed
40,974
$411,379,000
Sagimet Biosciences Inc
Opened
60,900
$330,078,000 0.28%
Pacific Biosciences Calif In
No change
75,300
$282,375,000 0.24%
Kinnate Biopharma Inc.
Closed
83,848
$198,720,000
AvroBio Inc
Opened
61,135
$78,253,000 0.07%
No transactions found
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